Yale Mouse Models
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Investigator |
Mouse Name |
Description |
Publication |
Contact |
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Janet L Brandsma |
HPV
Mouse Model |
A
Mouse Model of Human Papilloma Virus-induced
Disease |
J.
Virology 69:2716 |
|
Craig M Crews |
MetAP-2 |
Conditional
knockout of methionine aminopeptidase-2 |
PNAS |
|
Jack A Elias |
Inducible
VEGF |
Lung-specific
expression |
Nature
Med. 10:1095 |
|
Jack A Elias |
Leukemia
Inhib Factor |
Lung-specific
expression |
J.
Biol. Chem. 278:31226 |
|
Jack A Elias |
Constitutive
IL-10 |
Lung-specific
expression |
J.
Biol. Chem. 277:35466 |
|
Jack A Elias |
Inducible
IFNgamma |
Lung-specific
expression |
J.
Exp. Med 192:1587 |
|
Jack A Elias |
Constitutive
IL-13 |
Lung-specific
expression |
J. Clin Invest 103:779 |
|
Jack A Elias |
Inducible
IL-13 |
Lung-specific
expression |
J Clin Invest 106:1081 |
|
Jack A Elias |
Inducible
TGF-beta |
Lung-specific
expression |
J.
Exp. Med 200:377 |
|
Jack A Elias |
Constitutive
IL-11 |
Lung-specific
expression |
J. Clin Invest 98:2845 |
|
Jack A Elias |
Inducible
IL-11 |
Lung-specific
expression |
J. Clin Invest 100:2501 |
|
Richard A Flavell |
NFAT-Luciferase |
|
|
|
Richard A Flavell |
TLR3
(-/-) |
Knockout |
|
|
Richard A Flavell |
MKK3
(-/-) |
Knockout |
|
|
Richard A Flavell |
MKK6
(-/-) |
Knockout |
|
|
Richard A Flavell |
JNK 1
(-/-) |
Knockout |
|
|
Richard A Flavell |
MKK3
(-/-) MKK6 (-/-) |
Double
knockout |
|
|
Richard A Flavell |
IRAK-M
(-/-) |
Knockout |
|
|
Richard A Flavell |
TIRAP
(-/-) |
Knockout |
|
|
Richard A Flavell |
RIP2
(-/-) |
Knockout |
|
|
Richard A Flavell |
TLR5
(-/-) |
Knockout |
|
|
Richard A Flavell |
AP1-Luciferase |
|
|
|
Richard A Flavell |
RIP.B7/DQ8/MHC
Class II |
Knockout |
|
|
Richard A Flavell |
JNK 2
(-/-) |
Knockout |
|
|
Richard A Flavell |
Kv1.3 |
Knockout |
|
|
Richard A Flavell |
Nod2 |
Knockout |
|
|
Richard A Flavell |
foxp3-RFP
(FIR) |
Knock-in |
|
|
Richard A Flavell |
Tie-2
Cre recombinase |
Transgenic;
used to create conditional vcam-1 deficient mice |
|
|
Richard A Flavell |
TLR1
(-/-) |
Knockout |
|
|
Richard A Flavell |
TLR5
(-/-) |
Knockout |
|
|
Richard A Flavell |
TGF-beta
GFP KI |
Knock-in |
|
|
Richard A Flavell |
eGFP-IL10 |
Knock-in |
|
|
|
Wang
Min |
CCM3(PDCD10) |
Knockout |
|
|
|
Marina
Picciotto |
TetOp-beta2
transgenic |
Inducible
transgene for the beta2 subunit of nicotinic
acetylcholine receptor |
J
Neuroscience 23: 3837 |
|
|
Marina
Picciotto |
nestin-tTA
transgenic |
Nestin
promoter driving tetracycline transactivator 3 3 |
J
Comp Neurol 475:128 |
|
|
Marina
Picciotto |
CaM kinase I alpha KO |
alpha
isoform of calcium/calmodulin
dependent kinase I (early lethal) |
|
|
|
Shlomchik |
AM14 |
Produce
Rheumatoid Factor; Develop autoimmunity in predictable manner |
Immunity
19:837 |
|
|
Shlomchik |
CD20 |
Deplete
B cells in lupus-prone mouse model via expression of human CD20 |
|
|
|
Shlomchik |
VH186.2 |
|
Immunity
19:837 |
|
|
Shlomchik |
VH186.2L |
|
Immunity
19:837 |
|
|
Wei, Ning |
Csn2
(+/-) |
lacZ
insertion; Csn2+/- genotype has no phenotype |
Mol
Cell Biol. 23:6790 |
|
|
Zhang,
Hui |
SKP2 |
Prostate
cancer model (Prostate-specific SKP2 expression) |
Canc.
Res 63:1583 |
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