Yale Mouse Models |
| Investigator |
Mouse Name |
Description |
Publication |
Contact |
| Brandsma |
HPV Mouse Model |
A Mouse Model of Human Papilloma Virus-induced Disease |
J. Virology 69:2716 |
John Puziss (203) 785 6167 |
| Crews |
MetAP-2 |
Conditional knockout of methionine aminopeptidase-2 |
PNAS USA 103: 10379 |
David Fung (203) 436 3946 |
| Elias |
Inducible VEGF |
Lung-specific expression |
Nature Med. 10:1095 |
John Puziss (203) 785 6167 |
| Elias |
Leukemia Inhib Factor |
Lung-specific expression |
J. Biol. Chem. 278:31226 |
John Puziss (203) 785 6167 |
| Elias |
Constitutive IL-10 |
Lung-specific expression |
J. Biol. Chem. 277:35466 |
John Puziss (203) 785 6167 |
| Elias |
Inducible IFNgamma |
Lung-specific expression |
J. Exp. Med 192:1587 |
John Puziss (203) 785 6167 |
| Elias |
Constitutive IL-13 |
Lung-specific expression |
J. Clin Invest 103:779 |
John Puziss (203) 785 6167 |
| Elias |
Inducible IL-13 |
Lung-specific expression |
J Clin Invest 106:1081 |
John Puziss (203) 785 6167 |
| Elias |
Inducible TGF-beta |
Lung-specific expression |
J. Exp. Med 200:377 |
John Puziss (203) 785 6167 |
| Elias |
Constitutive IL-11 |
Lung-specific expression |
J. Clin Invest 98:2845 |
John Puziss (203) 785 6167 |
| Elias |
Inducible IL-11 |
Lung-specific expression |
J. Clin Invest 100:2501 |
John Puziss (203) 785 6167 |
| Flavell |
NFAT-Luciferase |
|
|
Hong Peng (203) 785 3074 |
| Flavell |
TLR3 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
MKK3 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
MKK6 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
JNK 1 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
MKK3 (-/-) MKK6 (-/-) |
Double knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
IRAK-M (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
TIRAP (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
RIP2 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
TLR5 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
AP1-Luciferase |
|
|
Hong Peng (203) 785 3074 |
| Flavell |
RIP.B7/DQ8/MHC Class II |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
JNK 2 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
Kv1.3 |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
Nod2 |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
foxp3-RFP (FIR) |
Knock-in |
|
Hong Peng (203) 785 3074 |
| Flavell |
Tie-2 Cre recombinase |
Transgenic; used to create conditional vcam-1 deficient mice |
|
Hong Peng (203) 785 3074 |
| Flavell |
TLR1 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
TLR5 (-/-) |
Knockout |
|
Hong Peng (203) 785 3074 |
| Flavell |
TGF-beta GFP KI |
Knock-in |
|
Hong Peng (203) 785 3074 |
| Flavell |
eGFP-IL10 |
Knock-in |
|
Hong Peng (203) 785 3074 |
| Min |
CCM3(PDCD10) |
Knockout |
|
Tracy Huang (203) 436 4933 |
| Picciotto |
TetOp-beta2 transgenic |
Inducible transgene for the beta2 subunit of nicotinic acetylcholine receptor |
J Neuroscience 23: 3837 |
John Puziss (203) 785 6167 |
| Picciotto |
nestin-tTA transgenic |
Nestin promoter driving tetracycline transactivator 3 3 |
J Comp Neurol 475:128 |
John Puziss (203) 785 6167 |
| Picciotto |
CaM kinase I alpha KO |
alpha isoform of calcium/calmodulin dependent kinase I (early lethal) |
|
John Puziss (203) 785 6167 |
| Shlomchik |
AM14 |
Produce Rheumatoid Factor; Develop autoimmunity in predictable manner |
Immunity 19:837 |
David Lewin (203) 785 6038 |
| Shlomchik |
CD20 |
Deplete B cells in lupus-prone mouse model via expression of human CD20 |
|
David Lewin (203) 785 6038 |
| Shlomchik |
VH186.2 |
|
Immunity 19:837 |
David Lewin (203) 785 6038 |
| Shlomchik |
VH186.2L |
|
Immunity 19:837 |
David Lewin (203) 785 6038 |
| Wei, Ning |
Csn2 (+/-) |
lacZ insertion; Csn2+/- genotype has no phenotype |
Mol Cell Biol. 23:6790 |
Tracy Huang (203) 436 4933 |
| Zhang, Hui |
SKP2 |
Prostate cancer model (Prostate-specific SKP2 expression) |
Canc. Res 63:1583 |
Tracy Huang (203) 436 4933 |