Yonas Isaak Tekle

(full CV)

Yale School of Medicine,

Department of Epidemiology and Public Health (EPH)

60 College Street.

New Haven, CT, 06510

Phone: +1 (203) 785-7353) Fax: +1 (203) 785-4782

E-mail: yonas.tekle@yale.edu; yonastekle@gmail.com

 

 

Education:

  • Post-Doctoral Associate: Yale University, EPH, CT, 2009 - present
  • Postdoctoral Research Associate, Smith College, 2006 - 2009
  • Ph.D., Uppsala University, 2006
  • Licentiate of Philosophy, Uppsala University, 2004

 

Research Interests:

  • Integrating Bioinformatics and Mathematical Modeling to understand the Epidemiology of Infectious Diseases (e.g. MRSA, Flu)
  • Assembling the Eukaryotic Tree of Life through Analyses of Eukaryotic Microbes
  • Taxonomy and Phylogeny of the Acoela (Metazoa, Bilateria)
  • Phylogeny of Basal Bilaterians

List of Publications:

(*equal contribution)

 

Tekle, Y. I., Parfrey L.W., Katz L.A. 2009. Molecular Data are Transforming Hypotheses on  the Origin and Diversification of Eukaryotes. BioScience 59: 471–481.

Grant, J., *Tekle, Y. I., Andersen O.R., Patterson D. J., Katz, L.A. 2009. Multigene evidence for the placement of a heterotrophic amoeboid lineage Leukarachnion sp. among photosynthetic stramenopiles. Protist, 160: 376 – 38.

Cole, J., Andersen O.R., Tekle Y. I., J. Grant, Katz L. A., Nerad T. A. 2009. Description of a New 'Amoebozoa' isolated from the American Lobster,  Homarus americanus (in press. Journal of Eukaryotic Microbiology)

Tekle, Y. I., Grant J., Cole J., Nerad T. A., Patterson D. J., Anderson O. R., Katz L. A. 2008. Phylogenetic placement of diverse amoebae inferred from multigene analysis and assessment of the stability of clades within "Amoebozoa" upon removal of varying fast rate classes of SSU-rDNA. Mol. Phylog. and Evol. 47: 339–352

Yoon, H. S., J. Grant*, Tekle, Y. I., M. Wu, B. C. Chaon, J. C. Cole, J. M. Logsdon, D. J. Patterson, D. Bhattacharya, L. A. Katz. 2008. A Broadly Sampled Multigene Tree of Eukaryotes. BMC Evolutionary Biology 8:14

Tekle, Y. I., Grant J., Cole J., Nerad T. A., Patterson D. J., Anderson O. R., Katz L. A. 2007. Multigene analysis of Corallomyxa tenera sp. nov. suggests its membership in a clade that includes Gromia, Haplosporidia and Foraminifera. Protist, 158: 457-472

Tekle, Y. I., Raikova O., Justine J-L.  and Jondelius U. 2007. Ultrastructure and Tubulin Immunocytochemistry of the Copulatory Stylet-like structure in Childia species (Acoela). Journal of Morphology 268(2):166-80.

Tekle, Y.I., Raikova, O, Justine, J-L, Hendelberg, J, Jondelius, U. 2007. Ultrastructural and immunocytochemical investigation of acoel sperms with 9 + 1 axoneme structure: new sperm characters for unraveling phylogeny in Acoela. Zoomorphology 126:1-16.

Raikova, OI, Tekle Y.I., Reuter M, Gustafsson MK, Jondelius U. 2006. Copulatory organ musculature in Childia (Acoela) as revealed by phalloidin fluorescence and confocal microscopy. Tissue Cell. 38(4):219-32.

Tekle, Y. I., Raikova O. and Jondelius U. 2006. A new viviparous acoel Childia vivipara sp. n. with observations on the developing embryos, sperm ultrastructure, body wall and stylet musculatures. Acta Zoologica 87: 121–130.

Ogunlana M. V., Hooge M. D., Tekle Y. I., Benayahu Y., Barneah O., and Tyler S. 2005. Waminoa brickneri n. sp. (Acoela: Acoelomorpha) associated with corals in the Red Sea. Zootaxa 1008: 1-11.

Tekle, Y. I., Raikova O., Ahmadzadeh A., and U. Jondelius. 2005. Revision of the Childiidae (Acoela), a total evidence approach in reconstructing the phylogeny of acoels with reversed muscle layers. J. of Zool. Systemat. Evol. Res. 43(1):72–90.

Tekle, Y. I. 2004. A new Haploposthia species (Acoela) from the Swedish west coast. Sarsia 89:85–90.

 

Manuscripts in review/preparation

(^ undergraduate author)

 

Tekle, Y. I., Townsend J.P., Teckle S, Galvani A. Modeling the transmission dynamics of MRSA genotypes with treatment and vaccination within hospital settings. (in prep.)

Tekle, Y. I., Grant J., ^ Kovner, A., Townsend J.P., Katz, L. Identification of new molecular markers for assembling the eukaryotic tree of life. (submitted to MPE)

Parfrey L.W., Grant J., Tekle, Y. I, Lasek-Nesselquist E., Morrison, H. G., Sogin M. L., Patterson, D. J., Katz, L.A. Broadly Sampled Multigene Trees Yield a Well-resolved Eukaryotic Tree of Life (submitted)

^ Lyman C., Tekle Y. I, Katz, L.A. Unusual Patterns of Genome Evolution in the Ciliate Clade Heterotrichea. (in prep. > 90% complete)

Tekle, Y. I., Hooge M. D., Maloy A. and Tyler S. Molecular phylogeny of the Haploposthiidae (Acoela). (in prep. > 60% complete)

 

Thesis works

 

Tekle, Y. I. (2006). Phylogeny and Taxonomy of Childia (Acoela): New characters for unraveling acoel phylogenies from molecules, ultrastructure, immunocytochemistry and confocal microscopy. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology; 140. 44 pp. Uppsala.

Tekle, Y. I. 2004. Evolution of the Acoela, with emphasis on the Childiidae, acoels with reversed body-wall musculature. (Licentiate Thesis, Department of Systematic Zoology, Evolutionary Biology Centre, Uppsala University).

Tekle, Y. I. 2002. Can Histone H3 alone or combined with 18S rDNA and Elongation factor 1-alpha solve the phylogenetic position of the Acoela (Master's Thesis, Department of Systematic Zoology, Evolutionary Biology Centre, Uppsala University).

Tekle, Y. I. 1997. Antimicrobial activity of seven selected medicinal plants. (Undergraduate thesis, Department of Biology, Asmara University)